Friday, September 2, 2022

Friday, September 2, 2022

Wednesday, August 31, 2022

Wednesday, August 31, 2022

Location: Liverpool, UK
Contract type: Permanent / Full Time
Closing date: Monday 17 October

The Role:
This leadership role is for a highly experienced scientist in evidence synthesis who will lead the further development of evidence synthesis, as part of the Global Health Trials and Synthesis Unit, and across the Liverpool School of Tropical Medicine and its partners.

The Department of Clinical Sciences is a global leader in evidence synthesis providing an excellent platform for translational research from concept through discovery and clinical trials to evidence synthesis, teaching, policy change and eventual health impact. 

Why join the department of clinical Sciences in this leadership post?
The post arises with the retirement of the Director of the Evidence Synthesis in Global Health Centre. It provides a great opportunity for an academic with experience in the area to develop and shape their own portfolio of methods, reviews and collaborative links with researchers and policy personnel. There is an existing infrastructure, with high quality and experienced grant managers, search specialists, a statistician, and post-master staff, and has funds and programmes of work running to April 2024. 

The Cochrane Infectious Diseases Group enabled pivotal reviews that led the evidence-base underpinning impregnated mosquito nets, artemisinin-based combination treatments, and a change in the formulation or oral rehydration salt solution. The work has been conducted as part of global collaboration within Cochrane and our own emerging evidence ecosystem. 

• Learn more and apply

Thursday, September 29, 2022 Category: Jobs

D-manoza (šećerne tablete) za sprječavanje ili liječenje infekcija mokraćnog sustava u odraslih i djece Što se proučavalo u ovom sustavnom pregledu? Infekcije mokraćnog sustava (IMS) vrlo su česte diljem svijeta. Najmanje 50% žena će jednom u životu imati IMS. Otprilike 15% do 25% odraslih i djece pati od ponovljenih i dugotrajnih infekcija mokraćnog sustava. Kod mnogih ljudi standardni antibiotici ne djeluju. D-manoza je šećer koji je dio normalne prehrane i vjeruje se da stvara neljepljivu površinu na stijenci mjehura, kao i oko bakterija. Smatra se da se bakterija tada izbacuje mokrenjem,...

Around 2.4 billion people globally are estimated to live with a health condition that could benefit from rehabilitation. Yet despite this high need, many people around the world are currently unable to access appropriate services.

Recognising this challenge, Cochrane has joined the World Rehabilitation Alliance (WRA), a World Health Organization (WHO) global network of stakeholders which aims to support the implementation of the Rehabilitation 2030 initiative by jointly advocating.

Cochrane Rehabilitation will lead our involvement in the WRA, given the team’s longstanding work in this topic area, and will contribute primarily to the research workstream.

Dr Carlotte Kiekens, Co-Director of Cochrane Rehabilitation, says:

“In order to strengthen and upscale rehabilitation in health systems worldwide, it is of utmost importance that rehabilitation interventions are based on evidence. The best available evidence on rehabilitation must be available and accessible in appropriate formats to all who need it.”

Cochrane Rehabilitation has collaborated with WHO to support the development of a robust evidence base to assist health policymakers for several years. They do this by providing synthesis and helping identify evidence gaps where high-quality research is needed. You can read more about their joint work in this interview with Cochrane Rehabilitation Director Professor Stefano Negrini.

Join the launch event – Tuesday 13 September, 14:00-15:00 CET

The WRA will formally launch during a virtual event on Tuesday 13 September. The event, which is free to attend and open to all, will introduce the WRA and why it has been established, and highlight some of the activities planned.

• Find out more about the event and register

Monday, August 29, 2022

Friday, August 26, 2022

Cochrane’s first open access journal, Cochrane Evidence Synthesis and Methods, has opened for submissions! Working in conjunction with our publisher, Wiley, this journal strengthens Cochrane’s ability to meet our stakeholders’ needs and publish different types of evidence synthesis beyond systematic reviews. It will also include methods research evaluating how evidence syntheses is planned, produced and disseminated, and research articles on critical areas for evidence synthesis, such as, priority setting, consumer involvement, and research integrity.  

Cochrane has over 100,000 members and contributors across an established global network who publish their systematic reviews in the Cochrane Database of Systematic Reviews. This new journal opens up opportunities for these members, and researchers new to Cochrane, to publish research outputs that go beyond Cochrane systematic reviews, which reflects the interests, talents and expertise of this global network and beyond. The journal aims to further develop the evidence base for how we produce and publish evidence synthesis, share best practice, case studies and commentaries.  

Michael Brown, Editor, Cochrane Evidence Synthesis and Methods (responsible for the content and development of the journal), and Professor at Michigan State University, USA, explains, “The agility involved means we can collaborate more closely with guideline developers, decision makers and funders through publication of evidence syntheses directly relevant to their specific interests. We hope the community is as excited as we are to be able to publish this range of research relevant to evidence synthesis in a journal with Cochrane’s philosophy for transparency, integrity, and independence.”

Karla Soares-Weiser, Editor-in-Chief, Cochrane, adds, “This is an exciting milestone for Cochrane as Cochrane Evidence Synthesis and Methods allows us to publish a wider range of evidence products that meets a more diverse range of stakeholder needs. It will enable Cochrane to better respond to important global health and social care needs and influence health decisions that go beyond the remit of systematic reviewing alone.”

Ella Flemyng, Editorial Product Lead, Cochrane, explains why this new journal is important for the field, “Cochrane Evidence Synthesis and Methods welcomes innovative ideas and is not afraid to trial new ways of publishing. This includes showcasing practices that support research integrity, embedding consumer involvement within the journal, piloting how to better visualise research, and improving peer review - as a few examples.”

For more information visit:

• Cochrane Evidence Synthesis and Methods
• How to submit your research 
• Learn more about our streamlined publishing process  
• Learn how to publish open access with Wiley 
• Contact cesm.office@wiley.com  

Tuesday, November 15, 2022

Thursday, August 25, 2022

Mogu li probiotici (živi mikroorganizmi) spriječiti infekcije gornjeg dišnog sustava, poput obične prehlade? Ključne poruke Probiotici mogu imati povoljan učinak u sprječavanju barem jedne pojave akutne infekcije gornjeg dišnog sustava, a vjerojatno su učinkoviti i u sprječavanju najmanje tri pojave infekcija gornjeg dišnog sustava. Potrebno je više istraživanja provedenih na starijim osobama. Potrebna su veća i dobro osmišljena istraživanja kako bi se mogle procijeniti koristi i potencijalne štetnosti primjene probiotika. Što su akutne infekcije gornjih dišnih puteva? Te infekcije uključuju...

Može li lijek za demenciju (memantin) pomoći osobama s poremećajem iz autističnog spektra? Dosadašnje spoznaje Poremećaj autističnog spektra (autizam) je bolest koja počinje u djetinjstvu. Osnovni simptomi uključuju trajne poteškoće u socijalnoj komunikaciji (npr. problemi u vođenju razgovora, komunikaciji bez riječi te otežano stvaranje i održavanje društvenih odnosa) i repetitivne te ograničene interese i ponašanja (npr. repetitivni manirizmi, ograničeno polje interesa i ponašanja, otpor promjenama i senzorne smetnje). Oko 1% do 2% djece ima autizam. Autistične osobe često imaju druge...

Glazba za nesanicu u odraslih Cilj sustavnog pregleda Ovaj Cochraneov sustavni pregled procijenio je učinke slušanja glazbe na nesanicu u odraslih i utjecaj čimbenika koji mogu utjecati na djelotvornost glazbe. Ključne poruke Utvrdili smo povoljan učinak glazbe na kvalitetu sna. Za sve ostale ishode nismo pronašli dovoljno kvalitetnih dokaza jer je bilo premalo sudionika, a ljudi koji su vršili bodovanje podataka bili su svjesni liječenja. Što je nesanica? Diljem svijeta, milijuni ljudi pate od nesanice. Mogu imati poteškoće s usnivanjem, održavanjem sna ili imaju slabu kvalitetu sna. Loš...

Monday, August 22, 2022

Monday, August 22, 2022

Smanjuje li uporaba tekućine za ispiranje usta prije stomatološkog zahvata rizik prijenosa infekcije s pacijenta na zdravstvenog djelatnika? Zašto je ovo pitanje važno? Mnogi stomatološki zahvati stvaraju kapljice koje se brzo talože na površini. Ako se koriste instrumenti velike brzine, kao što je bušilica, stvaraju se aerosoli koji se sastoje od sitnih čestica koje ostaju lebdjeti u zraku i koje se mogu udahnuti ili se talože dalje na površinama. Ovi aerosoli sadrže različite mikroorganizme i mogu prenijeti infekcije bilo izravnim kontaktom ili neizravno preko kontaminiranih površina. Kako...

Tenisice za trčanje za sprječavanje ozljeda donjih ekstremiteta pri trčanju kod odraslih Pitanje sustavnog pregleda Utječu li različite vrste tenisica za trčanje na rizik od nastanka ozljeda donjih ekstremiteta? Ključne poruke Neutralne tenisice ili one s ortopedskom potporom mogu dovesti do male ili nikakve razlike u broju trkača koji su zadobili ozljede ili u zadovoljstvu obućom u usporedbi s minimalističkim tenisicama. Nije sigurno smanjuju li tenisice s tehnologijom kontrole pokreta učestalost ozljeda, u usporedbi s neutralnim ili tenisicama s potporom. Tenisice sa mekim među-potplatom...

While medical research is the best source of information on which to guide treatment of health issues, fraudulent studies are an issue. Such research can skew the evidence base and even lead to harm, as well as damage trust in the scientific process.

Our Senior Research Integrity Editor, Lisa Bero, has recently written about this phenomenon in The Conversation US. In the article, she describes how systematic reviewers can be part of the solution and help to find such problematic studies. She also discusses research which she, Stephanie Boughton of the Cochrane Research Integrity team, and others have carried out about this.

Lisa explains: 

“Cochrane is actively involved in research and advocacy to promote independence, transparency, and integrity in healthcare research. While most research follows rigorous standards, studies with fake or fatally flawed findings are sometimes published. Cochrane and other systematic reviewers are in a unique position to be able to find and draw attention to these types of studies.”

• Read 'Fake research can be harmful to your health – a new study offers a tool for rooting it out'

What is Cochrane doing about this issue?

Cochrane has a policy in place that helps our reviewers spot problematic studies and decide what research to include and what to exclude in new reviews. When problems with medical research are so serious that the studies have to be withdrawn from publication, Cochrane also encourages our reviewers to go and back and mark where these studies have been included in reviews and, where necessary, update, amend or even withdrawn the review.

• Cochrane's policy on managing potentially problematic studies
• Learn more about Cochrane's Research Integrity work

Friday, August 19, 2022

A new Cochrane Library editorial has published titled 'Low sodium salt substitutes: a tool for sodium reduction and cardiovascular health.'

The World Health Organization has a target of reducing global population salt intake by 30% by 2025.  This has made Cochrane’s new systematic review on the efficacy and safety of low sodium salt substitutes (LSSS) timely.  The Cochrane systematic review and meta-analysis examines the evidence regarding the use of LSSS on cardiovascular health in adults and children and included blood pressure as a primary outcome.  

Rachael McLean, from the Department of Preventive and Social Medicine, University of Otago, New Zealand, discusses the latest Cochrane evidence and how it can support policymakers in their efforts to reduce sodium intake and how applicable the evidence may be in different settings and populations. 

Rachael McLean explains:

“In some countries, more than 50% of the salt intake comes from salt used in the home. Cochrane’s review of the evidence on low sodium salt substitutes is valuable for policy makers looking to make substantial impacts for cardiovascular health and in directing researchers where further studies are urgently needed.”

• Read the Cochrane Library Editorial 

 

Thursday, August 18, 2022

Friday, August 12, 2022