Anti-VEGF za sprječavanje komplikacija nakon vitrektomije kod proliferativne dijabetičke retinopatije Zašto je ovo pitanje važno? Proliferativna dijabetička retinopatija (PDR) je najnapredniji stadij komplikacije dijabetesa - dijabetičke retinopatije. Uzrokuju ga abnormalne nove krvne žile koje rastu na retini (mrežnici), sloju osjetljivom na svjetlost u stražnjem dijelu oka. Pars plana vitrektomija je široko prihvaćeno kirurško liječenje komplikacija PDR-a. Tijekom ove operacije uklanja se staklasto tijelo, želatinasta tvar koja postoji unutar oka. Najčešći razlog za izvođenje vitrektomije...

Utječe li broj doza pegilirane asparaginaze na preživljenje i rizik od toksičnosti? Istraživačko pitanje Koliko je asparaginaze, lijeka ključnog za liječenje raka krvi, akutne limfoblastične leukemije (ALL), optimalno kako bi se osiguralo najbolje moguće preživljenje dok se u isto vrijeme minimiziraju toksičnosti povezane s asparaginazom? Dosadašnje spoznaje Akutna limfoblastična leukemija podvrsta je raka krvi koja nastaje malignom transformacijom nezrelih bijelih krvnih stanica limfoidnog podrijetla. Akutna limfoblastična leukemija najčešći je karcinom u dječjoj dobi. Uporaba...

Title: Editorial Policy Lead
Specifications: Fixed term contract (six months with potential to extend to 12 months)
Salary:  £ 52, 000 per Annum
Location: Ideally based in the UK, Germany or Denmark. Candidates from the rest of the world will be considered; however, Cochrane’s Central Executive Team is only able to offer consultancy contracts outside these countries.
Directorate: Evidence Production and Methods
Closing date: June 18, 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high-quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Editorial Policy Lead will lead the development and implementation of editorial policies and related procedures for the Cochrane Database of Systematic Reviews and associated products. They will work closely with the Methods Support and Review Development team and Central Editorial Service to ensure that all content published on the Cochrane Library meets high standards of quality, accuracy, and transparency. Overall, this role will contribute to streamlining editorial policy procedures with a focus on author experience, to support Cochrane’s efficiency and sustainability as an organisation.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

• An opportunity to truly impact health globally
• A flexible work environment
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply"

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 18h June, 2023
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
•       Read our Recruitment Privacy Statement

 

Monday, May 29, 2023

Title: Legal Counsel
Specifications: Permanent Role (open to part-time minimum 4 days per week)
Salary: £55,256K per annum
Location: UK Remote (office in London is available if candidate wants to use it sometimes)
Directorate: Finance & Corporate Services
Closing date: 20 June 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high-quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production & Methods, Publishing & Technology, Development, and Finance & Corporate Services[CE1] .

The Legal Counsel will be required to provide legal advice across the organisation, to enable Cochrane to manage risk and meet its legal and regulatory obligations. The successful candidate will be a qualified solicitor with excellent communication skills, who can provide clear and pragmatic advice and manage their workload effectively whilst maintaining attention to detail.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.

You can expect:

• An opportunity to truly impact health globally
•  A flexible work environment
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply:

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 20 June 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Thursday, May 25, 2023 Category: Jobs

Early bird registration has been extended for the 2023 Cochrane Colloquium. Register by Wednesday 7 June 2023 to get the reduced early bird rate

You can register for the Cochrane Colloquium, which will take place at the Queen Elizabeth II (QEII) Centre in London from 4th to 6th September 2023, with Satellite events on 3rd September.

The Colloquium is an annual event for everyone with an interest in the use of evidence in healthcare decision making including those engaged in evidence production, co-production, dissemination, implementation, and policy making, as well as those making individual healthcare decisions.

This year’s theme is ‘Forward together for trusted evidence’. It will explore the challenges for the future around the trustworthiness of healthcare data and information whilst also celebrating 30 years of producing trusted evidence. 

You can explore the programme here and the list of plenary speakers here – with more to be added.

Students, healthcare consumers, and people from low-income, lower-middle-income, and upper-middle-income economies (LMIC) are eligible for a reduced rate.

Satellite events:

 On Sunday 3rd September, there are three satellite events taking place at the Colloquium venue that you may also like to register for:

• 2023 Cochrane Methods Symposium
• GRADE-CERQual event
• Putting evidence into practice: an event for students and healthcare professionals

 Find out more about these satellite events, including how to register, here.

Register today:

• Register here
• Registration fees – reduced early bird rate now ends on 07 June 2023
• Registration terms and conditions

Further information:

• Colloquium website 
• #CochraneLondon
• Press contact: Katie Abbotts, Cochrane UK
• Sign up for newsletter updates

Thursday, June 1, 2023

Thursday, May 25, 2023

Thursday, May 25, 2023

Wednesday, May 24, 2023

Pomažu li antidepresivi ljudima da prestanu pušiti? Što su antidepresivi? Antidepresivi su lijekovi i dodaci koji se koriste za liječenje depresije. Neki od njih su također bili testirani kako bi se utvrdilo mogu li pomoći ljudima da prestanu pušiti. Dva od ovih lijekova - bupropion (ponekad se naziva Zyban) i nortriptilin - ponekad se daju ljudima kao pomagala za prestanak pušenja. Cilj Cochraneovog sustavnog pregleda Pušenje duhana izuzetno je štetno za zdravlje ljudi. Za pušače, prestanak pušenja najbolja je stvar koju mogu učiniti za poboljšanje svog zdravlja. Mnogima je teško prestati...

Introducing "Las claves de la evidencia en salud" by Cochrane Iberoamerica—a dynamic Spanish course that delves into evidence-based healthcare, clinical trials, and Cochrane evidence. Designed for healthcare consumers (patients, care givers, family members), policy makers, and the healthcare team, this interactive course offers five modules, each estimated to take 30-40 minutes to complete. Best of all, it's completely free with a Cochrane account (registration for Cochrane account is also free).

The course offers interactive learning with reading materials, videos, quizzes, and other assessments. It follows the personal journey of 'Elena,' a fictional consumer, but participants can explore modules freely. It has been co-produced by healthcare consumers, researchers, and Cochrane specialists. The original English version, "Evidence Essentials", was translated and adapted by the Iberoamerican Cochrane Center.

"We are convinced that this course is a relevant and user-friendly contribution to disseminate to the Spanish-speaking public how we know if a treatment works and what is the process to generate scientific evidence for health care. At the Iberoamerican Cochrane Center we translate all Cochrane systematic reviews into Spanish and this new course in Spanish is an ideal addition to improve the use of all this evidence in health care", says Gerard Urrútia, director of the Iberoamerican Cochrane Center and the Iberoamerican Cochrane Network.

"We'll promote it in Spain and the 18 countries of the Iberoamerican Cochrane Network to enhance understanding of evidence in health," adds Urrútia. "It targets healthcare users and professionals, complementing other resources we provide."



"We are going to disseminate this course in Spain and in the other 18 countries that are part of the Iberoamerican Cochrane Network as a first gateway to learning the key elements of evidence in health," adds Urrútia. "Our target audience is not only health care users, but also all those who are not familiar with systematic reviews and need to make healthcare decisions, including healthcare professionals. These modules will also support the numerous resources and dissemination activities that we produce for the Spanish-speaking public, such as Nutrimedia or Cochrane responde."

Check out this free online resource in Spanish or the other three languages today! 

• Evidence Essentials
• Las claves de la evidencia en salud
• Evidenz verstehen - ein Onlinekurs von Cochrane
• Основы Доказательств Кокрейн

Tuesday, May 23, 2023

Programi koordiniranog liječenja za starije fragilne osobe u zajednici Ključne poruke • Programi koordiniranog liječenja za fragilne starije osobe u zajednici mogu dovesti do male ili nikakve razliku u ishodima pacijenata i usluga te troškovima povezanim s njegom. • Nema dovoljno dokaza koji bi opravdali bilo kakvu trenutačnu promjenu u praksi. • Potrebna su daljnja ispitivanja kako bi se utvrdilo koji su elementi ovih programa korisni. Zašto je ovaj sustavni pregled važan? Broj osoba koji žive s fragilnošću u dobi od 65 i više godina raste diljem svijeta. Ne postoji standardna definicija...

Monday, May 22, 2023

Koja je metoda najdjelotvornija u zadržavanju zuba u njihovom novom položaju nakon završetka terapije ortodontskim bravicama? Ključne poruke - Zbog manjka kvalitetnih dokaza nije moguće izvući čvrste zaključke o bilo kojem pristupu retenciji. - Potrebno je provesti više dobro osmišljenih istraživanja. Potrebno je mjeriti stabiliziranje zuba tijekom najmanje dvije godine, dugotrajnost trajanja udlaga, zadovoljstvo pacijenata i sve nuspojave udlaga, poput karijesa i bolesti desni. Što je proučavano u ovom sustavnom pregledu? Zubi se mogu ponovno iskriviti nakon ispravljanja ortodontskim...

Hlađenje tijela nakon reanimacije zbog srčanog zastoja Ključne poruke U ovom su pregledu autori istraživali dobrobiti za osobe koje su podvrgnute metodi hlađenja tijela na temperaturu od 32°C do 34°C nakon reanimacije zbog srčanog zastoja. Trenutni dokazi upućuju na to da konvencionalne metode hlađenja za induciranje hipotermije (niske tjelesne temperature) mogu smanjiti rizik od oštećenja mozga i poboljšati neurološke ishode (probleme sa živčanim sustavom) nakon uspješne reanimacije zbog srčanog zastoja. Što je srčani zastoj? Otprilike 30% do 50% ljudi koji boluju od koronarne bolesti srca...

It is with great sadness that we mark the passing of Hyeong Sik Ahn, Director of Cochrane Korea, Professor at the Department of Preventive Medicine, and former Dean of the Graduate School of Public Health at Korea University.

Professor Ahn's enduring relationship with Cochrane, spanning over twenty years, began when he attended his first Cochrane Colloquium in 2002. This initial gathering in Norway fueled his determination to introduce Cochrane principles in Korea. In 2007, Professor Ahn led the establishment of the Korean Branch of the Australasian Cochrane Center. Two years later, Cochrane Korea was officially inaugurated at Korea University as a geographical group of Cochrane.

Beyond his Cochrane-related activities, Professor Ahn organized the 8th Guidelines International Network Conference in the summer of 2011, themed "Linking Evidence, Policy, and Practice," marking the first time the conference was held in Asia. In 2014, he authored an influential article published in the New England Journal of Medicine titled "Korea's Thyroid Cancer 'Epidemic' – Screening and Overdiagnosis." This article highlighted Professor Ahn's determination to address overdiagnosis, particularly within the Korean healthcare system.

One of the highlights of Professor Ahn's academic career was hosting the 24th Cochrane Colloquium in the fall of 2016 in Seoul, where colleagues and researchers from around the world gathered for a successful conference that the Cochrane Korea team fondly remembers. In 2015, he spearheaded the implementation of the Choosing Wisely Korea campaign, aimed at reducing unnecessary medical tests and treatments in the country. By 2022, the campaign had gained endorsement from twenty-seven Korean medical societies.

"Professor Ahn played a pivotal role in establishing Evidence-Based Medicine in Korea," says Catherine Spencer, CEO of Cochrane. "To the fortunate students and colleagues who knew him, his passing represents an immeasurable loss. He will be deeply missed."

Professor Hyun Jung Kim, who served as co-director alongside Professor Ahn, will now assume the role of Director of Cochrane Korea, carrying forward Professor Ahn's inspiring legacy.

• Visit the Cochrane Korea website

 

 

 

Friday, May 19, 2023

Cochrane, a global independent network of researchers, professionals, patients, carers, and health enthusiasts, proudly announces the publication of its latest Special Collection titled "Cochrane at 30: what our 30th year can tell us about the future." 

In an era where access to health evidence has expanded, the risk of misinterpreting complex content has grown, while the likelihood of individuals obtaining a comprehensive and balanced understanding has diminished. Cochrane's role in providing accessible, credible information to support informed decision-making has never been more critical in improving global health.

At the heart of Cochrane's mission is the collaborative production of trustworthy health information devoid of commercial sponsorship and conflicts of interest. This commitment enables the generation of authoritative and reliable evidence, unconstrained by commercial and financial interests. Cochrane's systematic reviews, which gather and analyze the best available evidence, are recognized globally as the gold standard for reliable and high-quality information.

The need for Cochrane's work is even greater than it was when we started in 1993. In an era where access to health evidence has expanded, the risk of misinterpreting complex content has grown, while the likelihood of individuals obtaining a comprehensive and balanced understanding has diminished. Cochrane's role in providing accessible, credible information to support informed decision-making has never been more critical in improving global health.

To commemorate Cochrane's 30th anniversary, we have curated a collection of Cochrane Reviews that exemplify the enduring mission and innovative approaches taken by our organization. This special collection underscores the future of Cochrane, built upon its rich history of methodological diversity and unwavering dedication to meeting user needs.

• View the Cochrane Library Special Collection

 

 

Friday, May 19, 2023

Uravnotežene kristaloidne otopine u usporedbi s 0,9%-tnom fiziološkom otopinom za teško dehidriranu djecu s akutnim proljevom Što je dehidracija i kako se liječi? Djeci s akutnim proljevom ili gastroenteritisom koja dehidriraju potrebna je intravenska rehidracija tekućinama koja se naziva intravenska korekcija. Najčešće intravenske otopine koje se koriste u tu svrhu su takozvani kristaloidi, koji su otopine mineralnih soli (npr. elektroliti kao što su natrij, kalij ili klorid). Najčešće korišteni kristaloid za rehidraciju djece je 0,9%-tna fiziološka otopina. Nejasno je je li fiziološka...

Specifications: Permanent – Full Time (Hybrid Role, 3 days office and 2 days WFH)
Salary: £55,257 (Paid in DKK, as per market exchange rate) per annum
Location: Copenhagen, Denmark
Directorate: Publishing & Technology
Closing date: 7 June 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into five directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

As development team lead, you will manage an Agile/Scrum software development team (3 developers, 1 test engineer) who develop web applications that accelerate the production of systematic reviews of health evidence. You will support the team in their work, coordinate with product owners on timelines, and contribute to software testing within the team as needed to ensure sprint goals are met.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect:  

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here.
• The deadline to receive your application is 7 June 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Tuesday, May 23, 2023 Category: Jobs

Povećava li postavljanje cijevi za disanje pomoću videa (videolaringoskopija) uspješnost i sigurnost zahvata u novorođenčadi? Ključne poruke Videolaringoskopija može povećati uspjeh postavljanja cijevi za disanje u prvom pokušaju i može rezultirati manjim brojem pokušaja intubacije bolesne novorođenčadi, ali ne smanjuje samo vrijeme postavljanja cijevi. Videolaringoskopija najvjerojatnije dovodi do neznatno manjeg broja ozljeda dišnog puta novorođenčeta dok se cijev za disanje postavlja. Potrebna su bolja istraživanja kako bi shvatili ulogu videolaringoskopije u različitim područjima...

Thursday, May 11, 2023