Monday, August 21, 2023

Cochrane appoints new Governing Board interim Chair, Jordi Pardo Pardo and says farewell to two outgoing Trustees, Catherine Marshall and Tracey Howe

Cochrane is an international non-profit network, which sets the gold standard for synthesizing health research findings  to facilitate evidence-based health care.  Cochrane Reviews, found in the Cochrane Library, are up-to-date, follow a rigorous scientific methodology, and are free from commercial conflicts of interest. Health professionals, patients, and policy makers trust Cochrane Reviews for their healthcare decision-making. Cochrane works with researchers, health professionals, patients, policy makers, and media representatives from around the world to make Cochrane Reviews relevant and usable.

Cochrane's Governing Board is responsible for setting Cochrane's strategic direction and overseeing the work of the Chief Executive Officer, Editor in Chief, and Central Executive Team.

Cochrane’s Governing Board has appointed Jordi Pardo Pardo as new interim Chair. He will be taking over from Catherine Marshall and Tracey Howe who have been serving as Co-Chairs of the Board. Catherine's maximum four-year term will conclude in September 2023, and Tracey, whose term was set to end September 2024, has decided to step down this September due to personal circumstances.

Jordi Pardo Pardo, a longstanding member of the Board, former Managing Editor of Cochrane Musculoskeletal and current senior advisor with the Health Equity Thematic Network, will be taking over as interim Chair, effective from 5th September 2023. His appointment was made by the Governing Board during their May meeting. Jordi will serve in this role for a period of up to one year while a permanent Chair is recruited. The Governance and Nomination Committee will oversee the recruitment process and make a recommendation to the Board of Trustees.

Jordi’s tenure with Cochrane dates back to 1997 when he joined the Iberoamerican Cochrane Centre and contributed to the expansion of the Iberoamerican network. He has been part of the Lung Cancer group, the Equity Methods Group, Cochrane Canada and Cochrane Musculoskeletal, before joining the newly created Equity Thematic Network.

"I'm humbled by the opportunity to expand on the work that Tracey and Catherine have led to transform our organization. As we navigate into a new structure, I’m excited to explore the opportunities that a move to open access could bring to Cochrane and the world. I’m looking forward to working with our talented community to grow our reach and impact.”

- Jordi Pardo Pardo

Catherine Spencer, Cochrane CEO, extended a warm welcome to Jordi as interim Chair observing: “Jordi Pardo Pardo has an excellent understanding of both the workings of the Governing Board and the purpose of Cochrane. His appointment is welcomed by the Central Executive Team to ensure continuity as Catherine Marshall and Tracey Howe’s time comes to a close.”

She further expressed sincere gratitude to Catherine and Tracey for their unwavering dedication, leadership and invaluable contributions to Cochrane while wishing them all the best in their future endeavours.

• Learn more about Cochrane's governance and management

Tuesday, August 22, 2023

Specifications: Permanent – Full Time
Salary:  £60,000 per Annum (1.0 FTE)
Location: Remote – UK Based
Closing date: 04 September 2023

Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world. Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into four directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Head of Editorial Policy and Research Integrity is responsible for Cochrane’s editorial policies and research integrity and methods standards. They will ensure Cochrane’s review production processes and systems support efficient and trusted review production, with a focus on improving author experience. This role involves editorial and operational leadership, working closely with colleagues across the Evidence Production & Methods and Publishing and Technology directorates to ensure Cochrane’s product development aligns with its strategic priorities.   

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everything we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive on boarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here
• The deadline to receive your application is 04th Sep, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, August 21, 2023 Category: Jobs

Monday, August 21, 2023

Lijekovi za ublažavanje boli u djece s akutnom upalom srednjeg uha Ključne poruke - Trenutačni dokazi o učinkovitosti lijekova protiv bolova, samostalno ili u kombinaciji s drugim lijekovima, za ublažavanje boli u uhu u djece s akutnom upalom srednjeg uha su ograničeni. - I paracetamol (acetaminofen) i ibuprofen samostalno mogu biti učinkovitiji od placeba u ublažavanju kratkotrajne boli u uhu u djece s akutnom upalom srednjeg uha. Nismo sigurni postoji li razlika u učinku ibuprofena i paracetamola, ibuprofena koji se primjenjuje uz paracetamol te paracetamola koji se primjenjuje samostalno,...

Naočale sa zaštitom od plavog svjetla za sprječavanje zamora vida, kvalitetu spavanja i funkciju makule (žute pjege) Cilj Cochraneovog sustavnog pregleda Cilj ovog sustavnog pregleda bio je ispitati moguće povoljne učinke i sigurnost naočala sa zaštitom od plavog svjetla, poznate i kao naočale za računalo, na funkciju očiju, zaštitu makule i kvalitetu sna. Autori ovog sustavnog pregleda prikupili su i analizirali sva važna ispitivanja kako bi saželi najbolje dostupne znanstvene dokaze. Ključne poruke Naočale sa zaštitom od plavog svjetla vjerojatno ne smanjuju zamor očiju povezan sa radom na...

In healthcare, evidence-based information serves as the cornerstone of informed decision-making. Yet, the true impact of this knowledge lies in its accessibility and comprehensibility. Recognizing this, Cochrane China is running it's third annual competition that hopes to boost public interest in Cochrane reviews and fosters inventive pathways for sharing knowledge.

At the forefront of this endeavour is the Centre for Evidence-based Chinese Medicine at Beijing University of Chinese Medicine, a Cochrane China Network Affiliate that acts at the Translation and Dissemination Working Group. This Working Group, in collaboration with the Centre for Evidence-based Chinese Medicine of Beijing University of Chinese Medicine, the Cochrane China Network Affiliate acts as the Translation and Dissemination Working Group. This working group is jointly hosting the competition with the Center for Evidence-Based and Translational Medicine at Wuhan University, the Second School of Clinical Medicine at Wuhan University, and the dedicated members of the Cochrane China community.

Cochrane defines knowledge translation (KT) as the process of supporting the use of health evidence from our high-quality, trusted Cochrane reviews by those who need it to make health decisions. KT helps to make Cochrane evidence accessible and useful to everybody while advocating for evidence-informed health care.

We welcome you to submit a KT piece to this competition! 

Simplified Chinese: Submissions need to be in Simplified Chinese. If you start in a different language, you can always translate it. It is helpful if one person in your team can communicate in Simplified Chinese as most communication by organizations around the competition will be in this language. 
Open to all: All ages and geographical locations are welcome to enter.
Get creative: A wide range of creative formats is welcome;  past winners include pictures, written work, and videos. Some previous examples include this stop-motion video and these infographics.
Unite together: Participants can choose to submit their work either as individuals or as part of a team, allowing for diverse and collaborative contributions.
Deadline: The deadline for submissions is 30 August 2023. 
Winners: Winning submissions will be featured on the WeChat public website and the BUCM Essential Perspectives on Evidence-Based Medicine video channel. There are also branded prizes to be won!
Get in touch: Find out more information or  ask questions at ebmvolunteer@163.com

Join the WeChat account for more information: 

Monday, August 21, 2023

Koliko su učinkoviti hidrogelni oblozi u zacjeljivanju rana kože s koje su preuzeti presaci kože djelomične debljine? Ključne poruke - Ne znamo pomažu li hidrogelni oblozi (koji su dizajnirani da bi se rane održavale vlažnima) više od drugih obloga u zacijeljivanju rana s kojih su preuzeti presaci kože djelomične debljine (koža preuzeta s drugog dijela tijela). - Nismo pronašli nijedno istraživanje koje uspoređuje hidrogelne obloge s kremama, mastima ili drugim otopinama koje se primjenjuju izravno na ranu. - Potrebno je više istraživanja koja su bolje osmišljena da bi se odgovorilo na ovo...

Profilaktička primjena lijekova za razrjeđivanje krvi za sprječavanje smrti i venske tromboembolije kod bolesnika s bolesti COVID-19 koji ne trebaju liječenje u bolnici Ključne poruke ‐ Kada se koriste u izvanbolničkim uvjetima, antikoagulansi (lijekovi za razrjeđivanje krvi) vjerojatno smanjuju učestalost venske tromboembolije (VTE) i plućne embolije (PE) u usporedbi s placebom ili izostankom liječenja kod osoba s bolesti COVID-19. Međutim, čini se da ti lijekovi imaju mali ili nikakav učinak na smanjenje smrti, velikog krvarenja, potrebe za hospitalizacijom ili nuspojava. Što je venska...

Hiperbarična terapija kisikom za liječenje kasnih učinaka radioterapije Ključne poruke Kod odabranih ljudi i područja tijela hiperbarična terapija kisikom (HBOT, ebngl. hyperbaric oxygen therapy) može pomoći u rješavanju simptoma povezanih s kasnom ozljedom tkiva zračenjem (LRTI, engl. late radiation tissue injury), ali potrebna su daljnja istraživanja kako bi se utvrdilo koji ljudi mogu imati koristi od takvog liječenja i koje je najbolje vrijeme za njegovu primjenu. Koji se problemi javljaju nakon terapije zračenjem i kako ih liječiti? Postoji rizik od razvoja ozbiljnih komplikacija u...

Cochrane UK is gearing up to host the much-anticipated Cochrane Colloquium at London's Queen Elizabeth II Centre (QEII) from September 4th to 6th, 2023. The event promises an enriching experience, combining learning, networking, and fun. The countdown has begun, but there is still time to register!  

On Wednesday, September 6th, during the lunch break, join us for the #CochraneLondon Library of People. This event offers a unique opportunity to engage in conversations with human 'books,' who possess rich life experiences to share. This informal and enjoyable setup offers a refreshing way to connect with others and gain fresh viewpoints.

At the Library of People, you can "borrow" individuals as if they were open books, delving into their narratives and have conversations about subjects that intrigue you. These interactions will take place within small groups, enabling meaningful discussions. Each "book" will come with a list of suggested questions to facilitate the conversation's outset. 

The Cochrane Book Club members will be your "Librarians," guiding you in the selection and discovery of your ideal "book". You'll encounter a rich variety of "books," representing diverse nationalities, various career stages, roles within the Cochrane community, and personal passions.

Mentee to Mentor - crossing continents Omolola Alade 

15,000km southeast of home (Ibadan, Nigeria) I was first introduced to evidence synthesis during a graduate course on Epidemiology at the University of Sydney, Australia. I struggled with homesickness, but distracted myself by interpreting forest plots and critical appraisals of systematic reviews.

Several years later, this time 10,000km northwest of home, having mastered homesickness, I became a mentee of the US Cochrane network. Working with mentors moved me from my distant, hesitant interest to being an active contributor to evidence synthesis. Now I am leading a research project, with seven other mentees, on equity considerations in mentoring programs for evidence synthesis.

Back home in Nigeria, I am part of an inaugural collaborative initiative between my faculty and the Nigerian Institute of Medical Research to conduct several systematic reviews on oral health. I am also a mentor to the next generation of oral health researchers in evidence synthesis, mentoring three researchers in the first cohort of the National Oral Health for Development programme of the Nigerian Institute of Medical Research. So, as you can see I have gone from mentee to mentor as I have travelled the world.

 

Translating best evidence to support disaster settings - Evidence Aid (born in Cochrane in 2004) Claire Allen

Like many others I sat transfixed by the dreadful events which unfolded on 26 December 2004 in the wake of the Indian ocean earthquake and tsunami. Like many others, I had no idea what we as a society, or indeed Cochrane (which I’d worked with since 1997), could do, apart from giving money. Thankfully Mike Clarke who was Chair of the Board of Trustees in Cochrane and other colleagues had the inspired idea that as an organisation, Cochrane was perfectly placed to provide robust information to help those who were supporting the relief effort in making their decisions. And, boom, Evidence Aid was born. I jumped ship from Cochrane to Evidence Aid formally in 2014. From then, Evidence Aid became an independent charity, working with many organisations such as Save the Children, the Pan American Health Organization, the World Health Organization and we were at the forefront of the information provision when the recent Covid pandemic hit the world, starting our efforts in February 2020, before lockdowns were started.

 

My experience as an early career professional and Cochrane Ana Beatriz Pizarro

I am a 25-year-old early career registered nurse hailing from a small town in the north of Colombia. As a first-generation college student, I take immense pride in being the youngest editorial board member representing The Early Career Professionals Group. My passion for evidence-based healthcare is reflected in my extensive work, having published over 30 systematic reviews.

My primary goal is to improve lives in the Global South through multidisciplinary approaches, understanding specific health-disease problems, their impact, and potential applications in public health.

Beyond my professional pursuits, diverse interests add colour to my life, including singing, playing the ukulele, watching films, and finding joy in going to the beach and outdoor running.

I believe in the power of stories and have experienced their impact firsthand in my life. As a 'book' in the #CochraneLondon Library of People, I am eager to engage in conversations and share my life experiences, professional insights, and personal interests.

What have Hogwarts and Sherlock Holmes got to do with teaching EBM? Maria Björklund

I am a librarian at Cochrane Sweden who loves to read. Fantasy and detective stories are my favourite genres and I always enjoy how libraries and librarians are represented in fantasy and detective fiction!  I also am drawn in by how a mystery unfolds and you pick up clues and evidence (of course!) along the way and try to solve the crime or mystery yourself while reading.

I teach evidence-based medicine and refer to Sherlock Holmes and fictional libraries (like Hogwarts) when I am helping students understand evidence-based medicine and systematic data retrieval - it is a successful and engaging tactic.

 So, my reading preferences are sometimes also reflected in my professional work, and I think it is a nice way of engaging students in evidence- based medicine.

 A life-changing treatment decision: hope, fear and a bit of evidence? Sarah Chapman

I’ve had progressive hearing loss throughout my adult life and had got to the point where I was struggling to hear, despite hearing aids. In 2021, I was offered a potentially life-changing treatment, a cochlear implant. This would involve surgery and an irreversible process in which the ‘normal’ mechanism of hearing would be destroyed. People meeting the criteria for a cochlear implant are likely to benefit, but outcomes aren’t guaranteed and whether, how much, and in what ways I would benefit were uncertain. I learned first-hand that how we make treatment decisions in our real, messy lives doesn’t necessarily fit the neat models we see when we read about evidence-based decision-making.

Wikipedia: the world largest encyclopaedia - friend or foe? Jennifer Dawson

Communicating and sharing high-quality and reliable evidence informed information is a passion of mine. I have been working with Cochrane as our Wikipedian-in-Residence since 2016. The viewership of medical articles on English-language Wikipedia alone surpasses 2 billion page views per year and there are about 40,000 articles that relate to human health. 

In 2021, viewership of the main Wikipedia COVID-19-related article was over 500,000 views a month, far more than most of the other sources of information on the internet. Medical content is also available in over 280 languages. 

When I tell colleagues in my field that I help improve medical articles on Wikipedia, I usually get all sorts of interesting questions (and sometimes funny looks)! Why should we be considering Wikipedia? Do you recommend Wikipedia as a resource for people with questions about their health? How hard is it to edit Wikipedia? Many people in medical and evidence-based medicine fields find Wikipedia very frustrating. They are not wrong! There are many, many, articles that need improving and many that share incorrect, missing, or outdated information. It can be hard to jump in as a new editor and navigate conflict of interest and work with a very keen volunteer community of often anonymous editors. Rather than dismiss the ‘World’s Largest Encyclopedia’, why not learn more and potentially help improve what people are accessing!

Careless comms costs lives: battling misinformation on statins Harry Dayantis

 

There are few scientific topics as needlessly controversial as statins. These cholesterol-lowering drugs are prescribed to millions of people worldwide and have underdone countless trials evaluating their benefits and risks. There is an overwhelming scientific consensus that they reduce the risk of heart disease. So why do people get so worked up about them, and why do I care?

I care because my father died of a sudden heart attack overnight when I was at university. He was 49 years old and held national records for long-distance running. The post-mortem revealed that he had heart disease, and he might still be alive today if he’d been diagnosed and treated with statins. The risk has a significant genetic component, and I now take statins myself.

I’ve been involved in communicating many research papers on statins over the past decade, at UCL and Oxford University. I’ve worked with cardiologists and researchers to share the real evidence on statins in an often hostile media environment. It’s important that benefits and harms are communicated accurately so that people can make informed decisions; there is evidence that media scare stories have prevented many people from taking statins, potentially costing thousands of lives.

Accessibility at conferences shouldn’t just be a tick box Emily Messina

Attending or presenting at conferences is often an essential aspect of academic careers. We can share research and network, but let’s be honest, how many of us are mentally exhausted just planning to attend a conference, let alone after its over? Despite the fact that many of us, around 20%, are D/deaf, hard-of-hearing, disabled, and/or neurodivergent, we continue to leave accessibility as an afterthought. We strain to read slides or posters with tiny print, struggle with noise and sensory overload in crowded poster halls, forced to spend energy hunting for accessible paths through the conference space, and miss information that is only presented orally. Aren’t we tired of bare knuckling our way through conferences? Without creating content that's accessible, how can we have our science received, understood, and (importantly) acted on. So, let’s talk, share our experiences, and we can learn from each other better ways to improve accessibility and share our research more effectively.

Storytelling to break down boundaries Wanjiru Mwangi

Step into my world of communications and let me take you on an exciting journey about storytelling and the boundaries it breaks. Since time immemorial, storytelling has been a fundamental part of human connection. And in research, it has helped transcend the rigid confines of data and facts, transforming them into narratives that resonate with human emotions and experiences. Not by distorting truths or oversimplifying the complexities of research, but by transforming the most complex ideas into accessible information for those who truly need or yearn to grasp it. As you read through this, try and imagine the power of a personal story, a memory that resonates deeply, or a song that touches your heart. These diverse mediums of storytelling can foster deeper connections between researchers and their audience, leading to a more informed and enlightened public. So come chat with me, Wanjiru, a communications expert in both internal and external communications.

 Don't miss out on this exhilarating opportunity to engage with living stories. No pre-registration for Colloquium attendees is required; simply join us on the event day!

Library of People: Connecting Through Stories
Wednesday, September 6th
1:00 pm - 2:00 pm
Level 1, Pickwick

In addition to this Library of People event, we invite you to bring used books to Level 1 throughout the event. There will be a free book exchange table where you can pick up your next great read! 

Find out more about the Colloquium:

• View and update your schedule
• Visit the Colloquium website
• ‘Take a break' activities

Get in touch: colloquium@cochrane.org

Thursday, August 17, 2023

Friday, August 11, 2023

Intervencije za prihvaćanje preporuka utemeljenih na dokazima za akutni moždani udar Poboljšavaju li implementacijske intervencije pružanje skrbi temeljene na dokazima kod slučajeva akutnog moždanog udara? Ključne poruke Implementacijske intervencije su osmišljene kako bi poboljšale primjenu skrbi „utemeljene na dokazima”. Ona se odnosi na skrb za koju je u znanstvenim istraživanjima dokazano da pomaže ljudima s određenim zdravstvenim stanjem. Ne znamo vode li implementacijske intervencije u slučajevima akutnih moždanih udara do bolje primjene ove vrste skrbi. Potrebno je još istraživanja da...

Enteralno hranjenje sondom u osoba s amiotrofičnom lateralnom sklerozom, poznatom i kao bolest motoričkih neurona Ključne poruke Nismo pronašli randomizirana ili kvazi-randomizirana (djelomično randomizirana) kontrolirana ispitivanja koja uspoređuju upotrebu sonde za hranjenje s kontinuiranim hranjenjem na usta za osobe s amiotrofičnom lateralnom sklerozom (ALS) ili koja istražuju sigurnost i vrijeme različitih vrsta ili metoda postavljanja sonde za hranjenje kod osoba s ALS-om. ALS je najčešći oblik bolesti motoričkih neurona (engl. motor neuron disease, MND) i ta se dva pojma često koriste...

Specifications:  Fixed term maternity leave cover (through May 2024)
Salary: £43,000 Pro-rated 0.6 FTE (though 0.4 FTE will be considered)
Location: Remote - Candidates from the UK, Germany and Denmark with fixed-term employment contract. Candidates from the rest of the world with fixed-term consultancy contract.
Closing date: 20 Aug 2023
 
Cochrane is an international charity. For 30 years we have responded to the challenge of making vast amounts of research evidence useful for informing decisions about health. We do this by synthesising research findings and our work has been recognised as the international gold standard for high quality, trusted information.

Cochrane's strength is in its collaborative, global community. We have 110,000+ members and supporters around the world.” Though we are spread out across the globe, our shared passion for health evidence unites us. Our Central Executive Team supports this work and is divided into five directorates: Evidence Production and Methods, Publishing and Technology, Development, and Finance and Corporate Services.

The Learning and Support Officer will play a central role in revising and updating the Learning Team’s portfolio of author training materials, as Cochrane methods and processes change and evolve over the coming months. The Learning and Support Officer will also coordinate activities of the Cochrane Trainers’ Network, including communicating with the Network about updates to training materials and organizing train the trainers’ sessions for trainers from across the Cochrane Community. Given the geographically dispersed nature of Cochrane authors and trainers, this learning and support will be delivered remotely.

This role is part of the Learning Team, which is responsible for providing learning materials and training for Cochrane staff, authors, and users of Cochrane evidence. The team sits within the wider Membership, Learning and Support team, which strives to ensure that Cochrane recruits, develops and retains high quality contributors to participate in our work by providing a comprehensive service to engage new contributors, reward and develop existing contributors and support all members of our community when they need help.

Don’t have every single qualification? We know that some people are less likely to apply for a job unless they are a perfect match. At Cochrane, we’re not looking for “perfect matches.” We’re looking to welcome people to our diverse, inclusive, and passionate workplace. So, if you’re excited about this role but don’t have every single qualification, we encourage you to apply anyway. Whether it’s this role or another one, you may be just the right candidate.

Our organization is built on four core values: Collaboration: Underpins everting we do, locally and globally. Relevant: The right evidence at the right time in the right format. Integrity: Independent and transparent. Quality: Reviewing and improving what we do, maintaining rigour and trust.  

You can expect: 

• An opportunity to truly impact health globally  
• A flexible work environment  
• A comprehensive onboarding experiences
• An environment where people feel welcome, heard, and included, regardless of their differences

Cochrane welcomes applications from a wide range of perspectives, experiences, locations and backgrounds; diversity, equity and inclusion are key to our values.

How to apply

• For further information on the role and how to apply, please click here.
• The deadline to receive your application is 20th Aug, 2023.
• The supporting statement should indicate why you are applying for the post, and how far you meet the requirements, using specific examples. 
• Read our Recruitment Privacy Statement

Monday, August 7, 2023 Category: Jobs

Je li plesna terapija učinkovita za demenciju? Pregled dokaza Pitanje sustavnog pregleda Postoje li koristi od terapije plesom za ljude koji boluju od demencije? Ključne poruke Ne zna se je li terapija plesom učinkovita za demenciju. Potrebno je više istraživanja u ovom području, pogotovo o pitanju utjecaja koji plesna terapija ima na depresiju. Što je demencija? Demencija utječe na razmišljanje i pamćenje te na sposobnost ljudi u obavljanju svakodnevnih poslova. Također, dementni ljudi otežano sudjeluju u razgovorima, zbunjeni su i često mijenjaju raspoloženja. Ovi simptomi mogu utjecati na...

Postoji li razlika između vitrektomije pars plana s režnjem unutarnje membrane i vitrektomije pars plana s unutarnjim ljuštenjem membrane za veliku makularnu rupu? Ključne poruke 1. Pars plana vitrektomija s tehnikom režnja unutarnje membrane u usporedbi s pars plana vitrektomijom s unutarnjim ljuštenjem za liječenje makularnih rupa može dovesti do boljeg vida nakon tri ili više mjeseci. 2. Pars plana vitrektomija s tehnikom režnja unutarnje membrane u usporedbi s pars plana vitrektomijom s unutarnjim ljuštenjem membrane za makularne rupe vjerojatno dovodi do veće vjerojatnosti zatvaranja...

Prostaglandini za liječenje odraslih koji su bili podvrgnuti transplantaciji jetre Jesu li prostaglandini (lijekovi koji se daju za zaštitu jetre) korisni u liječenju odraslih koji su podvrgnuti operaciji transplantacije jetre? Ključne poruke Kod odraslih koji su imali operaciju transplantacije jetre, prostaglandini mogu smanjiti smrtnost zbog bilo kojeg uzroka, do mjesec dana nakon operacije, u usporedbi s placebom (lažnim liječenjem) ili standardnim liječenjem. Prostaglandini mogu dovesti do velikog smanjenja razvoja akutnog bubrežnog zatajenja koje zahtijeva dijalizu. Prostaglandini...

Koji lijekovi su najbolji za osobe sa suženjem karotidnih arterija (krvne žile koje dovode kisikom bogatu krv od srca do mozga)? Ključne poruke U usporedbi s placebom (inaktivnim lijekom): - varfarin, antikoagulant (lijek za razrjeđivanje krvi), može smanjiti rizik od razvoja nuspojava za 11%; - klortalidon, antihipertenziv (lijek za snižavanje visokog krvnog tlaka), može usporiti napredovanje stenoze karotide (suženja karotidnih arterija) za 55%. Potrebna su istraživanja koja uključuju veći broj sudionika te dugotrajnije praćenje rezultata kako bi se utvrdio najbolji medicinski postupak za...

Intervencije za sprječavanje ili smanjenje bubrežnih komplikacija u osoba s bolešću srpastih stanica Pitanje sustavnog pregleda Postoje li sigurne i učinkovite intervencije koje sprječavaju ili smanjuju bubrežne komplikacije kod osoba s bolešću srpastih stanica (BSS)? Dosadašnje spoznaje Bolest srpastih stanica ozbiljan je nasljedni poremećaj krvi u kojem se eritrociti (krvne stanice koje prenose kisik po tijelu) ne razvijaju normalno. Normalni eritrociti su fleksibilni i imaju oblik diska, dok su srpaste stanice krute i oblika polumjeseca. Ujedno, srpaste stanice su ljepljivije od normalnih...