Aggregator

Kombinirana oralna hormonska kontracepcijska pilula (OHK) u liječenju primarne dismenoreje

1 year 10 months ago
Kombinirana oralna hormonska kontracepcijska pilula (OHK) u liječenju primarne dismenoreje Istraživačko pitanje Cochraneovi autori pregledali su dokaze o učinkovitosti i sigurnosti kombiniranih oralnih hormonskih kontracepcijskih pilula (OHK-a) za liječenje bolnih menstrualnih grčeva (menstrualnih bolova, koji se nazivaju i dismenoreja). Dosadašnje spoznaje Kombinirane oralne hormonske kontracepcijske pilule (OHK) već se koriste za liječenje menstrualnih grčeva, ali dokazi o njihovoj učinkovitosti nisu bili uvjerljivi. Značajke istraživanja Pronađeno je 21 randomizirano kontrolirano...

Mjere za sprječavanje i smanjenje korištenja tjelesnih ograničenja u svim vrstama dugotrajne skrbi

1 year 10 months ago
Mjere za sprječavanje i smanjenje korištenja tjelesnih ograničenja u svim vrstama dugotrajne skrbi Što je proučavano u ovom sustavnom pregledu? Tjelesna (fizička) ograničenja su sredstva koja sprječavaju osobu da slobodno pomiče svoje tijelo u položaj po vlastitom izboru. Primjeri uključuju ograde za krevet, pojaseve i fiksne stolove koji sprječavaju ljude da ustanu iz kreveta ili stolice. Tjelesna ograničenja kod osoba s demencijom ili kod osoba koje ne mogu samostalno hodati su često korištena metoda u ustanovama za skrb ili čak u obiteljskim domovima. Glavni razlog za korištenje tjelesnih...

Interventions for preventing and reducing the use of physical restraints in all long-term care settings

1 year 10 months ago

Cochrane Review reveals vital role of supportive managers to minimise physical restraint use in care homes

A new Cochrane review finds that the use of physical restraints on care home residents can be reduced without increasing the risk of falls, when frontline care staff are empowered by supportive managers.

Physical restraints are devices that restrict freedom of movement and are frequently used in residential care homes, such as nursing homes and assisted living facilities. Examples are bed rails or belts that prevent residents from getting out of bed unassisted. These restraints are ethically problematic as they are mostly used in people with dementia who are often unable to consent to their use.

Physical restraints are often intended to prevent falls and fall-related injuries. However, the benefits are often small and come with important negative consequences. For example, the restriction of movement can have negative implications on physical functioning and mobility, actually increasing the risk of falls and care dependency. The measures can also trigger or increase fear or aggressive behaviour. For this reason, guidelines and experts recommend avoiding physical restraints in residential care settings.



But how can this be implemented in practice? A Cochrane Review, first published in 2011 and recently updated to reflect the latest research, analyses the scientific evidence on interventions and strategies to reduce the use of restraints. The team of authors, led by Ralph Möhler of the University Hospital Düsseldorf, identified 11 studies with a total of 19,003 participants, evaluating different intervention approaches.

In their evaluation, the authors found the best evidence for organizational interventions, which were investigated in 4 studies with a total of 17,954 participants. Organizational interventions to reduce the use of restraints consist of different components to function as a package. They aim to improve knowledge, skills, and strategies to prevent restraint use among both frontline care staff and managers. In three studies, employees designated as ‘champions’, were trained to develop and implement individual strategies to prevent the use of restraints within their facilities.  Managers supported this, including by relieving them of other activities and provide them with sufficient time for their tasks.

Such interventions probably reduce the number of residents with physical restraints in nursing homes by 14%. There was no overall change in the number of residents with falls or fall-related injuries and there was no increase in the prescription of psychotropic medication. In addition, there was no evidence of adverse effects of the interventions. Based on the study data, the authors calculated that the number of residents with physical restraints could be reduced from 274 to 236 per 1000 individuals, if such interventions were implemented. Focusing on changes on the organisational level seems to be important for achieving long-term effects.

Six studies examined educational interventions addressing staff knowledge and attitudes regarding the use of restraints. The results of these studies were inconsistent and some of the studies had methodological limitations. Therefore, no clear conclusion on the effects of educational interventions can be drawn.

"The results of this review show that physical restraints in nursing homes can be reduced without increasing falls or fall-related injuries,” Ralph Möhler, lead author of the review.

“There is no evidence in the reviewed studies that psychotropic medications were prescribed more often. However, education for frontline staff alone doesn’t seem to be enough; the support of care home managers plays a decisive role."

Friday, July 28, 2023
Lydia Parsonson

Blue-light filtering spectacles probably make no difference to eye strain, eye health or sleep quality

1 year 10 months ago

Spectacles that are marketed to filter out blue light probably make no difference to eye strain caused by computer use or to sleep quality, according to a Cochrane review of 17 randomised controlled trials of the best available evidence so far. 

Nor did the review, led by authors from the University of Melbourne and published in the Cochrane Database of Systematic Reviews, find any evidence that blue-light filtering lenses protect against damage to the retina, the light-sensitive tissue at the back of the eye.

Blue-light filtering lenses, also known as blue-light blocking spectacles, have been increasingly prescribed or recommended, often by opticians, since the early 2000s. An Australian survey-based study in 2018 found that, of the 372 optometrists who responded, 75% prescribed these lenses despite acknowledging limitations in the evidence to support their use.  

The Cochrane Eyes and Vision team set out to assess the effects of blue-light filtering lenses compared with non-blue-light filtering lenses for improving visual performance, providing protection to the retina and improving sleep quality. They analysed data from all the randomised controlled trials they could find on the topic and found 17 trials from six countries. Of the 17 trials, 12 were conducted in Australia, the Czech Republic, Japan, Norway, the USA and the UK. Five studies did not report the country in which the trial was conducted. Most of the studies were published after 2010, suggesting a growing research interest in blue-light filtering lenses over the past decade. The numbers of participants in individual studies ranged from five to 156, and the period of time over which the lenses were assessed ranged from less than one day to five weeks.

The senior author of the review is Associate Professor Laura Downie, Dame Kate Campbell Fellow and Head of the Downie Laboratory: Anterior Eye, Clinical Trials and Research Translation Unit, at the University of Melbourne, Victoria, Australia.

She said: “We found there may be no short-term advantages with using blue-light filtering spectacle lenses to reduce visual fatigue associated with computer use, compared to non-blue-light filtering lenses. It is also currently unclear whether these lenses affect vision quality or sleep-related outcomes, and no conclusions could be drawn about any potential effects on retinal health in the longer term. People should be aware of these findings when deciding whether to purchase these spectacles.”

However, the quality and duration of the studies also needs to be considered, she said. 

“We performed the systematic review to Cochrane methodological standards to ensure the findings are robust. However, our certainty in the reported findings is limited by the quality of the available evidence. The short follow-up period restricted our ability to consider potential longer-term outcomes.”

The first author of the review, Dr Sumeer Singh, a postdoctoral research fellow in the Downie Laboratory, said: “High-quality, large clinical research studies with longer follow-up in more diverse populations are still required to ascertain more clearly the potential effects of blue-light filtering spectacle lenses on visual performance, sleep and eye health. They should examine whether efficacy and safety outcomes vary between different groups of people and using different types of lenses.”

The review did not find any consistent reports of adverse side effects from using blue-light filtering lenses. Any effects tended to be mild, infrequent and temporary. They included discomfort wearing the spectacles, headaches and lower mood. These were likely to be related to the wearing of spectacles generally, as similar effects were reported with non-blue-light filtering lenses.

Prof. Downie said: “Over the past few years, there has been significant debate about whether blue-light filtering spectacle lenses have merit in ophthalmic practice. Research has shown that these lenses are frequently prescribed to patients in many parts of the world, and a range of marketing claims exist about their potential benefits, including that they may reduce eye strain associated with digital device use, improve sleep quality and protect the retina from light-induced damage. The outcomes of our review, based on relatively limited data, show that the evidence is inconclusive and uncertain for these claims. Our findings do not support the prescription of blue-light filtering lenses to the general population, and these results are relevant to a broad range of people, including eye care professionals, patients, researchers and the broader community.”

The potential mechanisms by which blue-light filtering lenses might be able to help with eye strain, sleep and protecting the retina are not known. One rationale for claims about the benefits of these lenses is that modern digital devices such as computers and smart phones emit more blue light than traditional lighting sources, and are being used for longer, and closer to bedtime. 

Dr Singh said: “The amount of blue light our eyes receive from artificial sources, such as computer screens, is about a thousandth of what we get from natural daylight. It’s also worth bearing in mind that blue-light filtering lenses typically filter out about 10-25% of blue light, depending on the specific product. Filtering out higher levels of blue light would require the lenses to have an obvious amber tint, which would have a substantial effect on colour perception.”

Monday, August 21, 2023
Muriah Umoquit

Kakvi su dokazi o tome da 'mikrougrušci' uzrokuju post-COVID-19 sindrom i je njihovo li uklanjanje pomoću plazmafereze opravdano?

1 year 10 months ago
Kakvi su dokazi o tome da 'mikrougrušci' uzrokuju post-COVID-19 sindrom i je njihovo li uklanjanje pomoću plazmafereze opravdano? Ključne poruke 1. Izraz 'mikrougrušci' nije ispravan izraz za čestice koje se ispituju kod osoba s post-COVID-19 sindromom, budući da to nisu ugrušci. Pojam 'čestice amiloid-fibrin(ogena)' je prikladniji. 2. Dokazi pokazuju da se čestice amiloid-fibrin(ogena) nalaze kod zdravih ljudi i onih s drugim bolestima, tako da nisu jedinstvene za stanje nakon COVID-19 bolesti. 3. Pacijenti ne bi trebali primati plazmaferezu za ovu indikaciju izvan konteksta...

Probiotici za sprječavanje nekrotizirajućeg enterokolitisa u nedonoščadi ili novorođenčadi s vrlo niskom porođajnom težinom

1 year 10 months ago
Probiotici za sprječavanje nekrotizirajućeg enterokolitisa u nedonoščadi ili novorođenčadi s vrlo niskom porođajnom težinom Cilj sustavnog pregleda Sprječava li davanje probiotika nedonoščadi ili dojenčadi s vrlo malom porođajnom težinom nekrotizirajući enterokolitis? Dosadašnje spoznaje Prijevremeno rođena dojenčad (ona rođena više od osam tjedana ranije) i dojenčad vrlo niske porođajne težine (ona koja pri rođenju teže manje od 1,5 kg) izložena su riziku od razvoja nekrotizirajućeg enterokolitisa, teškog stanja u kojem se tkiva u sluznici crijeva dojenčadi upale i počinju odumirati. Ovo...

Jesu li antitrombocitni lijekovi učinkoviti za osobe s bolešću COVID-19?

1 year 10 months ago
Jesu li antitrombocitni lijekovi učinkoviti za osobe s bolešću COVID-19? Ključne poruke Antitrombocitni lijekovi su skupina različitih lijekova koji mogu spriječiti potencijalno kobno stvaranje ugrušaka u krvnim žilama („trombotski događaji”). Za hospitalizirane pacijente s COVID-19 vjerojatno malo smanjuju trombotske događaje, ali vjerojatno ne utječu na smrt, kliničko pogoršanje ili poboljšanje bolesti COVID-19 u usporedbi s placebom ili standardnom skrbi. Međutim, antitrombocitni lijekovi mogu dovesti do blagog povećanja ozbiljnih neželjenih učinaka ('nuspojava') i vjerojatno povećati...

#CochraneLondon: A trailblazing conference prioritizing sustainability and environmental considerations

1 year 10 months ago

Cochrane UK is proud to host Cochrane’s Colloquium at the Queen Elizabeth II Centre (QEII) in London, UK from 4-6 September 2023. The countdown has begun, but there is still time to register and be part of this enriching experience! 

We spoke with Sabrina Khamissa, Cochrane's Event Support Officer, who shares the measures taken to create an environmentally responsible Colloquium. 

A central location with many transportation options
Hi Sabrina, we're thrilled about Cochrane's upcoming in-person event in London, UK, and the central location you've chosen is truly exciting. Can you share some insights into how the location was selected and its significance in terms of environmental considerations?

"Certainly! When deciding on the location for #CochraneLondon, we took several factors into account, including our community's geographical distribution. Since a substantial portion of our attendees are based in Europe, hosting the conference in the UK made sense as it encourages participants to opt for more sustainable travel options, particularly trains, which can significantly reduce the event's overall carbon footprint.

London was an ideal choice for its vibrant atmosphere and outstanding public transportation links. By placing the conference at the heart of the city, we aimed to minimize the need for private vehicles and promote the use of eco-friendly transportation alternatives. The venue's close proximity to multiple tube stations and pedestrian-friendly surroundings provides attendees with ample opportunities to choose greener commuting options. We invite all attendees to participate in the Anne Anderson Walk and see the many spots of medical history and London landmarks that are just steps away from the venue."

Sustainability at the heart of the venue choice
The Queen Elizabeth II Centre, where the Colloquium is set to take place, indeed appears to be a fantastic location. Can you elaborate on what specifically drew you to this venue and how its commitment to sustainability aligns with Cochrane's environmental goals?

"When looking at venues we had a checklist of specific requirements, placing a strong emphasis on environmental stewardship and a formal sustainability policy. The Queen Elizabeth II Centre stood out as an exceptional choice, impressing us with its diverse green initiatives aimed at ensuring minimal ecological impact. These initiatives encompass responsible waste management, energy-efficient systems, water conservation efforts, and even hosting 10,000 bees on the fourth-floor area—an inspiring commitment to urban biodiversity.

 

Attendees will see our venue choice play out in very practical ways. The Centre's strategic location allows easy accessibility, with the majority able to walk or use public transportation from their hotels. Moreover, we are dedicated to reducing single-use plastic, eliminating items like cups and straws during the event. By incorporating LED motion-sensitive lighting and maximizing natural light, energy conservation is prioritized. In our efforts to minimize paper usage, we will be using lots of digital signage ver printed signs, contributing to a more sustainable and eco-conscious conference experience for everyone at #CochraneLondon."

Delicious and environmentally friendly food choices
No matter the event, food selection and taste is always something attendees comment on afterwards. Is this something that was considered?

"It was! We understand that the dining experience is a significant aspect of any in-person event, and we wanted to ensure that attendees not only enjoyed delicious meals but also made environmentally conscious choices. The venue has a British-first policy for sourcing ingredients, to support local farms and growers but also to make sure they are using seasonal produce and are reducing carbon footprints.  Only fair-trade coffee and teas are served. And we have taken a step further by selecting a menu that emphasises plant-based meals and are going with 'bowl food' which helps reduce waste.

Rest assured, the taste and quality of the meals served at #CochraneLondon are of paramount importance to us, and we have thoughtfully selected food options that not only delight the taste buds but also align with our commitment to environmental responsibility."



A shift from traditional swag bags and branded items
It's really reassuring that a lot of thought has gone into many aspects of the venue and experience that are environmentally conscious. One typical aspect of an academic conference is swag or branded items that they get at the start of the conference. What can attendees expect?

"Rather than traditional swag bags, we've taken an eco-conscious route by introducing a print-on-demand store. This innovative approach allows attendees to curate their own experience by selecting and purchasing limited-edition Cochrane items beforehand. This not only reduces unnecessary waste but also ensures that participants receive merchandise they truly value and intend to use. The print-on-demand store offers an exciting range of items, including tote bags, t-shirts, and mugs, which attendees can choose to purchase for their convenience during the conference or as cherished souvenirs of the event.

Even the smallest details have been thoughtfully considered from an environmental perspective. When attendees arrive at the registration desk, they will receive a lanyard and name badge. Here, too, we have opted for a sustainable approach, providing recyclable name badges that will be printed on location. This decision further minimizes our ecological footprint while ensuring that attendees can proudly display their identification throughout the conference in an eco-friendly manner."


We hope you enjoyed this insightful glimpse into #CochraneLondon's integration of sustainability. By showcasing how even the simplest choices can culminate in a profound impact, the Cochrane Colloquium sets a noteworthy example for fostering greener and more responsible event experiences worldwide. 

Join us at #CochraneLondon as we unite to propel our shared vision and build a more sustainable world, advancing together for trusted evidence. See you there!

Monday, July 31, 2023
Muriah Umoquit

Get ready for the 2023 Cochrane Colloquium: view the full programme and build your schedule

1 year 10 months ago

Cochrane UK is proud to be hosting Cochrane’s Colloquium at the Queen Elizabeth II Centre (QEII) in London, UK from 4-6 September 2023. The countdown has begun, but there is still time to register and be part of this enriching experience! 

You can now explore the full programme and curate your own Colloquium experience. Take advantage of this opportunity to select the sessions you're most eager to attend and tailor your schedule to your needs and interests. Though it won't guarantee you a seat, it will help us allocate the bigger rooms for the most popular sessions. Once you have picked your sessions, you can add your chosen session to your Apple, Google, or Outlook calendar.

With the theme “Forward together for trusted evidence”, the 2023 Cochrane Colloquium is set to be a groundbreaking event, uniting individuals from diverse backgrounds in a journey of learning, networking, and unforgettable experiences. Immerse yourself in a captivating lineup of plenary talks, workshops, posters, oral presentations, and meetings that encompass a vast spectrum of topics and issues in evidence-based health care.

The colloquium isn't just about the academic content – it's about building connections and creating unforgettable memories. Engage in enriching networking events, ‘take a break’  with some fun social activities, and discover the wisdom of human 'books' at our thought-provoking Library of People. You'll also have the chance to join your colleagues and new Colloquium friends at an unforgettable social gathering at the iconic Natural History Museum. This event truly has something remarkable for everyone!



"Cochrane Colloquiums are more than just an academic gathering; they are a celebration of progress, collaboration, and camaraderie," says Sabrina Khamissa, Cochrane's Event Support Officer.  "The #CochraneLondon program is a testament to this spirit, offering a diverse and engaging lineup of sessions led by some of the most prestigious experts globally. From groundbreaking methodology in evidence synthesis to insightful discussions on knowledge translation, there's something for everyone. We are thrilled to welcome you all to this transformative experience that will shape the future of Cochrane and evidence-based healthcare on a global scale. Together, let's forge ahead for trusted evidence and make a lasting impact on the world of healthcare!"

As anticipation builds, we can't wait to welcome you to London and unite the community once again! Don't miss out on this transformative event, where trusted evidence takes center stage and lasting connections flourish.

Find out more:

Get in touch: colloquium@cochrane.org

Tuesday, July 25, 2023
Muriah Umoquit

Connect, learn, and thrive: Students and early career professionals set for an inspirational experience at #CochraneLondon

1 year 10 months ago

Cochrane UK is hosting Cochrane’s Colloquium at the Queen Elizabeth II Centre (QEII) in London, UK from 4-6 September 2023. With the theme “Forward together for trusted evidence”, the 2023 Cochrane Colloquium is set to be a groundbreaking event with a mix of learning, networking, plenary speakers; a unique and memorable experience at one of London's most renowned venues.

At Cochrane, nurturing aspiring minds and supporting professionals embarking on their career journey is part of the work we do. Our commitment is evident through initiatives like the Cochrane Early Career Professionals Network, Cochrane US Mentorship,  Cochrane International Mobility, and the student pathway to Cochrane Membership. Among these opportunities, the Cochrane Colloquium stands out as an inspirational experience not to be missed. This three-day event provides an enriching platform to learn, connect, and grow. Delve into a diverse range of sessions and engaging activities, fueling your knowledge and expanding your professional network in the world of evidence-based healthcare.

Exciting sessions relevant to students and early career professionals: 

  • Putting evidence into practice - A satellite event for students and healthcare professionals: A half-day event on the Sunday ahead of the Colloquium. Learn about Cochrane Reviews, evidence-based practice, fraudulent research and trustworthy evidence. This interactive event is for students and healthcare professionals from any healthcare discipline that feels there is a gap in their current skill set. You may register just for this event or add this event to your colloquium experience. 
  • Meet the Cochrane CEO and Editor-in-Chief - Networking doesn't get any more exciting than this! Meet some of the top people in Cochrane, ask questions, and interact in a casual environment. 
  • Meet the Author Journey Lead - Find out more about how to propose a new or updated review, and what the topic experts that consider proposals are looking for.
  • Forward Together: new ways to participate in Cochrane - Learn about all the many ways you get in involved in Cochrane's ecosystem!
  • Cochrane-Wikipedia Initiative - Join this hands-on workshop to help improve the health content that people are accessing online.
  • Interpreting systematic review findings - Join this small-group workshop to learn about how to translate research and support decision-making in health care. 
  • Library of People - Just like a regular library where you check out books, come along to speak to someone you wouldn’t normally meet and listen to their story.

This is just a small section of the diverse programming offered at Cochrane London. There are plenty of short oral sessions, longer plenary sessions, posters, social events, and workshops. Over three days you will be able to immerse yourself in the latest advancements in systematic review methodology and network with the leading experts in evidence-based medicine. 

Don't miss out on this unique opportunity to be part of Cochrane's Colloquium and contribute to the pursuit of trusted evidence. Register today and let's move forward together towards a healthier future! 

Cochrane Colloquium
4-6 September 2023
London, UK
Registration fees with information about student discount and one-day registration
Full programme

 

Tuesday, August 1, 2023
Muriah Umoquit

#CochraneLondon brings ‘posh bash’ to iconic Natural History Museum

1 year 10 months ago

Cochrane UK is hosting Cochrane’s Colloquium at the Queen Elizabeth II Centre (QEII) in London, UK from 4-6 September 2023. With the theme “Forward together for trusted evidence”, the 2023 Cochrane Colloquium is set to be a groundbreaking event with a mix of learning, networking, plenary speakers; a unique and memorable experience at one of London's most renowned venues. On the evening of Tuesday, September 5th, delegates will gather at the iconic Natural History Museum in South Kensington, for an extraordinary social event.

After the museum closes its doors to the public, Cochrane Colloquium attendees will be granted exclusive access to the main entrance area, Hintze Hall. This hall has dramatic Romanesque arches and a majestic staircase. You’ll have the opportunity to explore the surrounding museum specimens in the Hall and dance beneath the suspended 25-meter blue whale skeleton named ‘Hope’.

In the spirit of giving back, Cochrane Colloquium organizers have requested a £15 donation during registration, to be given to St. Mungo's, a national charity based in London that works to prevent homelessness and aid individuals in their journey to recover from it. By encouraging donations, we hope to minimize non-attendance and food waste, while positively impacting the community.

"One of the most anticipated aspects of every Cochrane Colloquium is the opportunity to gather with colleagues, share laughter, and dance the night away,” says Martin Burton, Director of Cochrane UK. “We are excited to host this year's social event at the Natural History Museum, which sets the stage for an unforgettable evening. Prepare to be captivated by the perfect blend of British charm, vibrant UK music, and the sheer delight of coming together with colleagues. We are confident that this year’s social event will create cherished memories for all who join us!"

The dress code is slightly ‘posher’ than the conference – so deerstalker hats and fascinators are welcome! Attendees will enjoy some delicious bowl food and canapés while the dance floor beckons. Embracing the tradition of previous Colloquiums, participants will sway to music representative of the host country. UK is rich in music tradition, from regency ballroom Contra Dancing to British punk rock. No prior dance experience is necessary; simply join in the fun on the dance floor!

Attendees can look forward to immersing themselves in the rich history and grandeur of the venue, enjoying the vibrant atmosphere, and creating lasting memories alongside colleagues from around the world. To get attendees excited and ready to dance the night away, an exclusive Spotify playlist has been created for #CochraneLondon. You can also contribute your favourite UK songs on social media using the event's official hashtag, #CochraneLondon. 

Cochrane Colloquium Social Event 
Tuesday 5 September 2023
7:30 pm
Natural History Museum
Address: Cromwell Rd, South Kensington, London SW7 5BD, UK
Provided: Bowl food, canapés, desserts, drinks
Dress Code: posh/spiffy casual
Guests: If you would like to bring guests, you’re welcome to buy additional tickets at £75 each (including VAT). To do so, please email registration@cochrane.org and let them know how many extra tickets you would like.

•       Visit the Colloquium website

Friday, July 28, 2023
Muriah Umoquit

Doprinose li kontrolni pregledi ultrazvukom očuvanju funkcije noge i održavanju otvorenosti arterije nakon kirurških zahvata na arterijama donjih ekstremiteta?

1 year 10 months ago
Doprinose li kontrolni pregledi ultrazvukom očuvanju funkcije noge i održavanju otvorenosti arterije nakon kirurških zahvata na arterijama donjih ekstremiteta? Ključne poruke Zbog nedostatka čvrstih dokaza, prednosti intenzivnih kontrola dupleks ultrazvukom (DUZV) nakon revaskularizacije donjih udova nisu jasne. Nijedno istraživanje nije prijavilo štetne događaje povezane s dupleks ultrazvukom. Koje su prednosti kontrole dupleks ultrazvukom? Opstrukcija ili suženje velikih arterija donjih udova, poznato kao aterosklerotska bolest donjih udova ili periferna arterijska bolest, može zahtijevati...

News from Cochrane UK

1 year 10 months ago

Founded 30 years ago in Oxford, Cochrane UK was Cochrane’s first geographic group. Cochrane now has over 130 such groups across the world, working in-country to support the production, dissemination and use of evidence to guide decision-making in health and care.

In March 2024, Cochrane UK’s current contract with the National Institute for Health and Care Research (NIHR), hosted by the Oxford University Hospitals NHS Foundation Trust, will come to an end. As a result, Cochrane UK will shortly be seeking a new funder and host institution.

Catherine Spencer, Chief Executive of Cochrane, said: “Cochrane UK has been at the forefront of Cochrane throughout its 30 year history and was our first geographic group. Cochrane UK has made an extraordinary contribution to evidence-based health and care, I extend my heartfelt thanks to the incredible team in Oxford – past and present – for all they have done.

“As we look to the future, there is an exciting opportunity for a new institution to host Cochrane UK and help more people to benefit from health and care evidence. We will be reviewing what is needed in the UK before we begin a selection process. But I would encourage anyone interested in hosting Cochrane UK at their institution to get in touch with me in the meantime.”

Last November it was announced that in September 2023, Cochrane UK’s Director, Martin Burton, will be moving to Cambridge to become Master of Sidney Sussex College. This summer, Therese Docherty will take on the role of Acting Director, having managed Cochrane UK’s operations for nine years.

Catherine Spencer said: “Martin’s exceptional leadership at Cochrane UK has been truly inspiring. His dedication to advancing evidence-based healthcare and improving patient outcomes has left an indelible mark on our organization and the broader medical community. He has shown a peerless talent for fostering collaboration, supporting people and driving impactful work. As he embarks on the next chapter, we extend our heartfelt gratitude for his invaluable contributions and wish him all the best with his new role.”

Martin Burton said: “I have thoroughly enjoyed my time as Director of Cochrane UK, in particular for the opportunity it has given me to work with an excellent team here, and with so many wonderful Cochrane contributors in the UK and around the world. Cochrane UK is in safe hands and I look forward to hearing more about Cochrane’s future plans. The world needs high-quality evidence in general, and synthesised evidence in particular, now more than ever before. These are exciting times as Cochrane adapts and flexes to meet the new challenges ahead.”

Wednesday, July 19, 2023
Harry Dayantis

Lijekovi za snižavanje krvnog tlaka za odrasle s ranim stadijima kronične bubrežne bolesti (bez dijabetesa)

1 year 10 months ago
Lijekovi za snižavanje krvnog tlaka za odrasle s ranim stadijima kronične bubrežne bolesti (bez dijabetesa) O čemu se radi u ovom sustavnom pregledu? Kronična bubrežna bolest (KBB) je dugotrajno stanje koje se javlja kada su bubrezi oštećeni. Važno je dijagnosticirati i liječiti KBB u ranim stadijima kako bi spriječili ili odgodili ozbiljnije stadije kronične bubrežne bolesti (dijaliza ili transplantacija). Osobe s kroničnom bubrežnom bolesti izložene su riziku od kardiovaskularnih bolesti (bolesti srca i pluća). Zabilježeno je da lijekovi za snižavanje krvnog tlaka mogu smanjiti ili...

Percepcije i iskustva zdravstvenih radnika o integraciji primarne zdravstvene zaštite: pretražni pregled kvalitativnih dokaza

1 year 10 months ago
Percepcije i iskustva zdravstvenih radnika o integraciji primarne zdravstvene zaštite: pretražni pregled kvalitativnih dokaza Što je integracija primarne zdravstvene zaštite? Integracija primarne zdravstvene zaštite je način kombiniranja različitih usluga primarne zdravstvene zaštite koje su se prethodno pružale odvojeno. Obično je cilj ove integracije dati ljudima bolji pristup zdravstvenoj skrbi i učinkovitije koristiti ograničene zdravstvene resurse. Zašto je važno znati stavove i iskustva zdravstvenih radnika? Integracija primarne zdravstvene zaštite provodi se u mnogim zemljama s...

Rana nazalna intermitentna ventilacija s pozitivnim tlakom (NIPPV) naspram ranog nazalnog kontinuiranog pozitivnog tlaka u dišnim putevima (NCPAP) za nedonoščad

1 year 10 months ago
Rana nazalna intermitentna ventilacija s pozitivnim tlakom (NIPPV) naspram ranog nazalnog kontinuiranog pozitivnog tlaka u dišnim putevima (NCPAP) za nedonoščad Pitanje sustavnog pregleda Pruža li NIPPV veće kratkoročne i dugoročne koristi bez ugrožavanja nedonoščadi s respiratornim distresom ili rizikom od respiratornog distresa u usporedbi s NCPAP-om? Dosadašnje spoznaje Nazalna intermitentna ventilacija s pozitivnim tlakom (engl. nasal intermittent positive pressure ventilation, NIPPV) može povećati učinkovitost nazalnog kontinuiranog pozitivnog tlaka u dišnim putevima (engl. nasal...

Koje su dobrobiti i rizici korištenja statina za žene sa sindromom policističnih jajnika koje ne planiraju trudnoću?

1 year 10 months ago
Koje su dobrobiti i rizici korištenja statina za žene sa sindromom policističnih jajnika koje ne planiraju trudnoću? Ključne poruke 1. Nejasno je poboljšavaju li statini redovitost menstruacije, poboljšavaju li hirzutizam (pretjerana dlakavost) i smanjuju li količinu akni (prištići) i razinu testosterona (muški spolni hormon). 2. Nijedno istraživanje nije proučavalo spontanu ovulaciju. 3. Moguće je da statini ne povećavaju rizik od neželjenih učinaka, ali malo je dokaza koji to potvrđuju. Što je sindrom policističnih jajnika? Žene sa sindromom policističnih jajnika (engl. polycystic ovary...

Koje strategije mogu utjecati na to koliko precizno i koliko dugo osobe s cističnom fibrozom provode fizioterapiju prsnog koša i tjelovježbu?

1 year 10 months ago
Koje strategije mogu utjecati na to koliko precizno i koliko dugo osobe s cističnom fibrozom provode fizioterapiju prsnog koša i tjelovježbu? Dosadašnje spoznaje Cistična fibroza (CF) je progresivno i ograničavajuće genetsko stanje koje utječe na mnoge sustave u tijelu, posebno na pluća. U Ujedinjenom Kraljevstvu, jednoj na svakih 2500 beba dijagnosticira se CF. Fizioterapija je vrlo važan dio liječenja za osobe s cističnom fibrozom. Dva glavna cilja fizioterapije prsnog koša su uklanjanje ljepljive sluzi iz dišnih puteva kako bi se spriječile ponovljene infekcije i oštećenje pluća te...

Kontinuirani povišeni pritisak zraka u dišnim putevima za liječenje apneje u nedonoščadi

1 year 10 months ago
Kontinuirani povišeni pritisak zraka u dišnim putevima za liječenje apneje u nedonoščadi Ključne poruke Nismo pronašli niti jedno ispitivanje koje je usporedilo CPAP (engl. continuous positive airway pressure, metodu neprekidnog povećanog pritiska u dišnim putevima) s potpornom njegom za apneju u nedonoščadi. Pronašli smo četiri ispitivanja koja su uspoređivala različite vrste CPAP-a. Ispitivanja su bila mala, a postoji mogućnost da je na pruženu skrb zdravstvenih djelatnika utjecala spoznaja o vrsti liječenja koje je pojedino dijete primilo. Stoga, na temelju ovih ispitivanja ne možemo...

Vedolizumab u postizanju i održavanju remisije Crohnove bolesti

1 year 10 months ago
Vedolizumab u postizanju i održavanju remisije Crohnove bolesti Ključne poruke – Vedolizumab je učinkovit u postizanju i održavanju remisije kod osoba s Crohnovom bolešću u usporedbi s placebom (lažnim liječenjem). – Osobe koje primaju vedolizumab vjerojatno nisu sklonije pojavi neželjenih reakcija od osoba koje primaju placebo, a neće imati ni veću sklonost pojavi ozbiljnih neželjenih reakcija tijekom postizanja ili održavanja remisije. Koji je cilj ovog sustavnog pregleda? Crohnova bolest je kronično upalno stanje koje zahvaća gastrointestinalni trakt (crijeva). Vedolizumab se naziva...